According to the Office for National Statistics (ONS), about 25 people in private homes in England had Covid-19 in the week to March 5, or 2.1 million people.
This is up from one in 30, or 1.9 million people, in the past week, and comes after three consecutive weeks where infections were estimated to have been high in England.
In contrast, Scotland has now seen an increase in infection levels for six weeks in a row, with 299,900 people likely to contract the coronavirus last week, the equivalent of one in 18.
This is the highest figure for Scotland since estimates began in autumn 2020, according to an analysis by the PA news agency.
The previous record was 297,400 people in the first week of this year.
Both Wales and Northern Ireland saw a jump in spread last week, after a period of falling infections, from 94,200 people for Wales to 97,900, one in 30, and Northern Ireland from 106,300 people to 143,800, one in 13.
Across Britain, 2.6 million people were estimated to have the coronavirus last week, up from 2.4 million.
The number stood at 4.3 million at the start of the year.